The complete bending energy function for nicked DNA

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Published 28 March 2011 Europhysics Letters Association
, , Citation Hao Qu and Giovanni Zocchi 2011 EPL 94 18003 DOI 10.1209/0295-5075/94/18003

0295-5075/94/1/18003

Abstract

We derive an analytic expression for the bending elastic energy of short DNA molecules, valid in the entire range from low to high energies. The elastic energy depends on three parameters: the length of the molecule (2L), the bending modulus B, and a critical torque τc at which the molecule develops a kink. In the kinked state, the elastic energy is linear in the kink angle, i.e. the torque at the kink is constant (=τc). τc depends (weakly) on the sequence around the nick, but is about 27 pN×nm. We measure it for a specific sequence, through experiments where the elastic energy of constrained DNA molecules is directly measured.

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10.1209/0295-5075/94/18003